Epidermolysis Bullosa (EB) is a group of inherited Bullous disorders characterized by formation of blistering following minor trauma (Nikolksy Sign), healing with scarring. It is caused by one or more mutations in at least one of 20 different genes that synthesize structural proteins that are involve in adherence of epidermal to dermis. We observed and cared for a 2 day old female neonate with low birth weight, normal antenatal history who presented at birth with spontaneous bullous skin eruptions to parts of skin of the upper and lower limbs which ruptured with minor mechanical trauma. She had conservative care and even though there was lack of finances for genetic test to pinpoint the mutated gene the wounds healed with acceptable scar. We are glad to share this rare condition with the scientific world.

Introduction: lower lid malposition following malignancy surgery in infra- orbital area is often challenging and any way to reduce its chance is appreciated. Case presentation: 36 years old women with confirmed Basal Cell Carcinoma (BCC) of left cheek underwent tumor excision with free margins and remained skin defect reconstructed with adipocutaneous v-y advancement flap, which designed in a horizontally orientation. Patient had no signs of ectropion with good wound repair and obscured scar. Conclusion: v-y flaps are commonly used local flaps with minimal donor site morbidity, and if designed horizontally, not only may reduce chance of lower lid malposition, but also can remain more acceptable scars.

Aggressive Fibromatosis (AF) is a rare, benign neoplasm originating from musculoaponeurotic stromal structures characterized by aggressive growth and infiltration of local tissues. To date, there are only six previously reported cases of AF involving the larynx. Our case involves a 70-year-old female with a 5-year history of hoarseness and an enlarging neck mass consistent with aggressive recurrent fibromatosis. MRI showed a large, solid mass arising from the left anterior cervical space displacing the trachea and upper airway to the right. A year after the initial radical resection, the patient presented with recurrence. A second radical excision was performed not including a laryngectomy. Radiation therapy was consulted for possible local treatment to prevent subsequent recurrence of tumor. Literature has reported up to 40-70% recurrence rates of AF within 18 months. There is minimal literature to guide treatment. Surgery seems to be the treatment of choice for head and neck AF, but management of recurrence is controversial.

A 30–year man was referred to our institution for progressive bilateral keratoconjunctivitis following toxic epidermal necrolysis. Slit-lamp examination showed an elevated, red, vascularized lesion covering the entire cornea. The lesion was removed by superficial lamellar keratectomy. The histopathological findings confirmed the diagnosis of corneal pyogenic granuloma. These uncommon lesions usually develop in adults after minor trauma or surgery. To our knowledge, this is the first reported case of corneal pyogenic granuloma related to toxic epidermal necrolysis

Aortocaval fistulas are a rare cause of high output heart failure. The infrequency with which it is encountered makes these fistulas a formidable diagnostic and treatment challenge. In the absence of infection, traditional repair with open surgical approach has required in-situ graft replacement of the affected portion of the aorta with concomitant repair of the cava defect. Mortality associated with open repair is reported to be as high as 66%. Technical advances in endovascular treatment of aortic aneurysms over the past two decades are increasingly used in other large vessel pathologies. This mini-review summarizes current evidence for employing endovascular techniques for aortocaval fistulas.